Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.
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Nasal discharge was seen in 11 out of 13 cases but only 2 patients have actually complained about it. Nasocaring, this upstaging did not prevent total excision surgically with the approach that was planned prior to surgery.
Orbital decompression was done to resolve proptosis.
Radiotherapy is usually reserved to patients with intracranial extension of disease where complete surgical excision may not be possible. Strayer; Emanuel Rubin The infratemporal fossa approach for nasopharyngeal tumors.
Unfortunately, this is difficult due to innocuous presenting symptoms. Received Apr 24; Accepted Jun 6. Medical treatment and radiation therapy are only of historical interest.
Anterior bowing of the posterior maxillary wall, due to invasion of the pterygomaxillary space on axial CT, known as the Holman-Miller sign is one of the characteristic findings. On examination, it may be seen as a pale reddish-blue mass. Diagnostic and therapeutic bleia.
In our study we dealt with 2 patients with recurrent disease [ 18 ]. MRI is used posttreatment to detect residual or recurrent tumor mass and to monitor the effects of radiotherapy. A wait and watch policy with periodic imaging may thus postpone or eliminate the need for surgery and reduce morbidity. Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. J Otolaryngol Head Neck Surg. He also nasofarin of difficulty in breathing since 6—7 months.
This tumor originates in the lateral wall of the nasal cavity, close angiodibroma the superior border of the sphenopalatine foramen. Orbital involvement through infraorbital angiofibgoma case no.
Pterygopalatine fossa was invaded in 3 patients. A history angiofibeoma head ache was given by 6 patients case nos. In these entire patients, ipsilateral maxillary artery was found to be the major feeding vessel.
Preoperatively, all the three patients were embolized and this step seems to be helpful for endoscopic approach to prevent intraoperative hemorrhage. True facial deformity was not a complaint in any of the patients but case no.
The classification nassofaring clinical staging is relatively easy and helps to plan treatment and determine prognosis. The prevalence in males may be explained by high androgen receptor AR expression suggesting that JNA is androgen dependent. Androgen receptor, juvenile angiofiborma, nasopharyngeal angiofibroma.
Case 6 Case beliw.
Juvenile nasopharyngeal angiofibroma
Views Read Edit View history. Blood vessels were seen in large number at the periphery of the lesion [ Figure 5 ]. However, since a vast majority of the cases do occur between 14 and 25 years of age, this term is retained.
It accounts for 0. Histopathology reveals a fibrocellular stroma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern.
The patients were treated surgically using various surgical approaches like trans-palatal, endoscopic trans-nasal, lateral rhinotomy and trans-maxillary approach depending on their JNA stage. Intracranial extension can however occur.
Contrast enhance CT scan belis JNA extending into left sphenoid sinus eroding the lateral wall of sphenoid and entering the cavernous sinus area with intracranial extradural extension.
JNA’s sex selectivity and the relatively young nasofarig at diagnosis suggest that its development is hormone dependent. Thank you for updating your details. It presents as an innocuous, painless, unilateral nasal obstruction with or without epistaxis and rhinorrhea. See staging of juvenile nasopharyngeal angiofibromas. W B Saunders Co. Support Center Support Center. Age of the patient and stage of the JNA at presentation are the two most important factors in predicting the recurrence of JNA.
Nasopharyngeal angiofibroma – Wikipedia
Xngiofibroma of JNA is made by complete history, clinical examination, radiography, nasal endoscopy; and specialized imaging techniques such as arteriography, CT, and magnetic resonance imaging MRI. JNA is an uncommon, highly vascular, locally invasive, unencapsulated tumor with a distinct predilection for an origin in the nasopharynx of adolescent males. Numerical sex chromosome aberrations in juvenile angiofibromas: Macroscopically this tumor appears as a rounded, circumscribed, noncapsulated mucosa covered mass.
Irradiation may be an option if surgery is not possible or only incomplete nsaofaring achieved 2,4,6. National Center for Biotechnology InformationU.
It most commonly affects adolescent males and may grow into fissures of the skull and may spread to adjacent structures.