In vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni was .. and characterization of polyphenol oxidase from leaves of Cleome gynandra L. Food . Protective effect of standardized extract of Cleome viscosa against Animals; Anti-Ulcer Agents/administration & dosage; Anti-Ulcer. Research Journal of Pharmacognosy and Phytochemistry. Delivering full text access to the world’s highest quality literature.

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Total phenol and flavonoid content in the extracts were determined spectrophotometrically.

He has published and presented papers in reputed National and International journals and conferences. Animals were allowed to recover and stabilize in individual cages and were deprived of water during postoperative period.

Phytochemical Screening and Anti-Ulcer Activity of Cleomo Gynandra Linn

Research Journal of Pharmacognosy and Phytochemistry Year: From the present study results reveals the antiulcer activity of ethanol extract leaves which is comparable to that of Omeprazole.

Mol Nutr Food Res.

However, most of these treatments produce adverse reaction such as hypersensitivity, arrhythmia, impotence, gynecomastia, and hematopoietic disorders. Ethanol EBG was screened for antiulcer anttiulcer in pylorus ligation-induced ulcer models in Wistar rats. Conflicts of interest There are no conflicts of interest. The photometric evaluation of the antioxidant capacity of the ethanolic EBG leaves showed good antioxidant capacity [ Figure 3 ].


High amount of flavonoids was found in EBG. The seeds and its oil have antihelminthic properties but they are ineffective in treating roundworm infections.

Antiulcer Herbs

NO radical antihlcer of EBG was carried out as previously described. Peptic ulcer is a digestive disorder most commonly found in clinical practice. Reagent blank was prepared using distilled water. The fresh leaves of the B.

The ethanol extracts showed good antioxidant capacity in DPPH radical scavenging assay and NO radical scavenging activity when compared to standard.

clwome An aqueous seed extract displayed significant analgesic activity in mice and local anaesthetic activity in guinea pigs. The roles of phytochemicals in bronchial asthma. Farombi EO, Fakoya A. After incubation for 90 min at room temperature, the absorbance against the reagent blank was determined at nm on spectrophotometer with a preprepared gallic acid calibration curve from 0.

Antiulcer Herbs

In vitro antioxidant activity of the extracts was tested using 2,2-diphenylpicrylhydrazyl DPPHnitric oxide NO radical scavenging activity. Thus, the objective of the present investigation was to evaluate in vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni leaves extract EBG. Extract obtained by Soxhlation showed higher total phenolic and flavonoid contents. The results of the histopathological investigation of Barleria gibsoni leaves for antiulcer effects using pylorus ligation induced ulcer model in rats laid credence to traditional use of the plant leaves in ulcer treatment.


One milliliter of Folin—Ciocalteu phenol reagent was added to the mixture and shaken.

The experiment was done in triplicate. Innov Food Sci Emerg Technol. The ethanol extract of leaves demonstrated increase in percentage preventive index compared to omeprazole respectively. The ulceration in gastric mucosa was measured and scored. Journal List Pharmacognosy Res v.

Flavonoid content and antioxidant activities from Cinnamomum species. National Center for Biotechnology InformationU.

NO is a potent pleiotropic mediator of physiological processes such as neuronal signaling, smooth muscle relaxant, regulation of cell-mediated toxicity, and inhibition of platelet aggregation. The ability of DPPH radical scavenging was higher in the EBG even significantly lower than standard ascorbic acid thus proving strong antioxidant potential of B.

On pylorus ligation-accumulated secretions and the related ulcers confirm gastric acid output to be the basic cause of gastric ulcers.